antiobesityresearch.com/surgery

Surgery: Peripheral nerves

Target

Method

Company [references]

Thoracic N Stimulation Leptos Biomedical [personal communication]

Vagus N VBloc EnteroMedics [1,2]

References

1. Camilleri M, Toouli J, Herrera MF, Kulseng B, Kow L, Pantoja JP, Marvik R, Johnsen G, Billington CJ, Moody FG, Knudson MB, Tweden KS, Vollmer M, Wilson RR, Anvari M. Intra-abdominal vagal blocking (VBLOC therapy): clinical results with a new implantable medical device. Surgery. 2008 Jun;143(6):723-31.

2. Warne JP, Foster MT, Horneman HF, Pecoraro NC, de Jong HK, Ginsberg AB, Akana SF, Dallman MF. The gastroduodenal branch of the common hepatic vagus regulates voluntary lard intake, fat deposition, and plasma metabolites in streptozotocin-diabetic rats. Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E190-200.

Surgery: Gastrointestinal tract

References

Borg CM, le Roux CW, Ghatei MA, Bloom SR, Patel AG, Aylwin SJ. Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety. Br J Surg. 2006 Feb;93(2):210-5.

Bult MJ, van Dalen T, Muller AF. Surgical treatment of obesity. Eur J Endocrinol. 2008 Feb;158(2):135-45.

de Fatima Haueisen Sander Diniz M, de Azeredo Passos VM, Diniz MT. Gut-brain communication: how does it stand after bariatric surgery? Curr Opin Clin Nutr Metab Care. 2006 Sep;9(5):629-36.

Holdstock C, Zethelius B, Sundbom M, Karlsson FA, EdŽn Engstršm B. Postprandial changes in gut regulatory peptides in gastric bypass patients. Int J Obes (Lond). 2008 Nov;32(11):1640-6.

Karamanakos SN, Vagenas K, Kalfarentzos F, Alexandrides TK. Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study. Ann Surg. 2008 Mar;247(3):401-7.

Le Roux CW, Welbourn R, Werling M, Osborne A, Kokkinos A, Laurenius A, Lšnroth H, FŠndriks L, Ghatei MA, Bloom SR, Olbers T. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg. 2007 Nov;246(5):780-5.

Moo TA, Rubino F. Gastrointestinal surgery as treatment for type 2 diabetes. Curr Opin Endocrinol Diabetes Obes. 2008 Apr;15(2):153-8.

Rubino F, Forgione A, Cummings DE, Vix M, Gnuli D, Mingrone G, Castagneto M, Marescaux J. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg. 2006 Nov;244(5):741-9.

Swarbrick MM, Stanhope KL, Austrheim-Smith IT, Van Loan MD, Ali MR, Wolfe BM, Havel PJ. Longitudinal changes in pancreatic and adipocyte hormones following Roux-en-Y gastric bypass surgery. Diabetologia. 2008 Oct;51(10):1901-11.

Vincent RP, le Roux CW. Changes in gut hormones after bariatric surgery. Clin Endocrinol (Oxf). 2008 Aug;69(2):173-9.

Warne JP, Padilla BE, Horneman HF, Ginsberg AB, Pecoraro NC, Akana SF, Dallman MF. Metabolic and neuroendocrine consequences of a duodenal-jejunal bypass in rats on a choice diet. Ann Surg. 2009;249(2):269-76.

Morinigo R, Vidal J, Lacy AM, Delgado S, Casamitjana R, Gomis R. Circulating peptide YY, weight loss, and glucose homeostasis after gastric bypass surgery in morbidly obese subjects. Ann Surg. 2008 Feb;247(2):270-5.

Reinehr T, Roth CL, Schernthaner GH, Kopp HP, Kriwanek S, Schernthaner G. Peptide YY and glucagon-like peptide-1 in morbidly obese patients before and after surgically induced weight loss. Obes Surg. 2007 Dec;17(12):1571-7.

Bond DS, Phelan S, Leahey TM, Hill JO, Wing RR. Weight-loss maintenance in successful weight losers: surgical vs non-surgical methods. Int J Obes (Lond). 2009 Jan;33(1):173-80.

Trakhtenbroit MA, Leichman JG, Algahim MF, Miller CC 3rd, Moody FG, Lux TR, Taegtmeyer H. Body weight, insulin resistance, and serum adipokine levels 2 years after 2 types of bariatric surgery. Am J Med. 2009 May;122(5):435-42.

Zhang H, DiBaise JK, Zuccolo A, Kudrna D, Braidotti M, et al. Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2365-70.

Cummings DE. Endocrine mechanisms mediating remission of diabetes after gastric bypass surgery. Int J Obes (Lond). 2009 Apr;33 Suppl 1:S33-40.

Cummings DE. Gastric bypass and nesidioblastosis--too much of a good thing for islets? N Engl J Med. 2005 Jul 21;353(3):300-2.

Laferrre B, Heshka S, Wang K, Khan Y, McGinty J, Teixeira J, Hart AB, Olivan B. Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes. Diabetes Care. 2007 Jul;30(7):1709-16.

Sjostrom L, Narbro K, Sjšstršm CD, Karason K, Larsson B, Wedel H, Lystig T, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007 Aug 23;357(8):741-52.

Thaler JP, Cummings DE. Minireview: Hormonal and metabolic mechanisms of diabetes remission after gastrointestinal surgery. Endocrinology. 2009 Jun;150(6):2518-25.